Sensitization of spinal cord nociceptive neurons with a conjugate of substance P and cholera toxin
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چکیده
منابع مشابه
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15 صفحه اولSubstance P decreases a potassium conductance of spinal cord neurons in cell culture.
Substance P (SP) produced membrane depolarization and decreased membrane conductance of mouse spinal cord neurons in primary dissociated cell culture. SP-responses were abolished by intracellular tetraethylammonium suggesting that SP decreased potassium conductance. Reversal of SP-responses was not observed with membrane hyperpolarization suggesting that SP reduced a voltage-dependent potassium...
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ژورنال
عنوان ژورنال: BMC Neuroscience
سال: 2007
ISSN: 1471-2202
DOI: 10.1186/1471-2202-8-30